BACKGROUND AND OBJECTIVES: This study compares seizure outcomes and complication rates between open corpus callosotomy (CC) and laser interstitial thermal therapy (LITT) CC in adult and pediatric patients with medically refractory generalized epilepsy. Although CC is a palliative option for nonresectable foci, the efficacy and safety of LITT CC compared with open CC remain unclear....

Implantable neurotechnologies are increasingly used to reduce seizure burden in pediatric epilepsy. Vagus nerve stimulation (VNS), the most common option, is effective for only half of patients, with no means to predict outcome prior to surgery. As a result, many children undergo invasive and costly procedures without benefit. Although T1-weighted magnetic resonance imaging (T1w) is routinely...

Originally introduced for epilepsy surgery, awake brain surgery is now frequently used for resection of brain tumors. In such cases, it allows for a more extensive and safer resection of supratentorial lesions in highly eloquent areas, such as motor, sensory, and language regions. We present the case of a 22-year-old, right-handed woman who underwent awake surgery...